Complete Sequences of mcr-1-Harboring Plasmids from Extended-Spectrum-β-Lactamase- and Carbapenemase-Producing Enterobacteriaceae.

نویسندگان

  • Aiqing Li
  • Yong Yang
  • Minhui Miao
  • Kalyan D Chavda
  • José R Mediavilla
  • Xiaofang Xie
  • Ping Feng
  • Yi-Wei Tang
  • Barry N Kreiswirth
  • Liang Chen
  • Hong Du
چکیده

Here we completely sequenced four mcr-1-haboring plasmids, isolated from two extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli and two carbapenemase-producing Klebsiella pneumoniae clinical isolates. The mcr-1-harboring plasmids from an E. coli sequence type 2448 (ST2448) isolate and two K. pneumoniae ST25 isolates were identical (all pMCR1-IncX4), belonging to the IncX4 incompatibility group, while the plasmid from an E. coli ST2085 isolate (pMCR1-IncI2) belongs to the IncI2 group. A nearly identical 2.6-kb mcr-1-pap2 element was found to be shared by all mcr-1-carrying plasmids.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 60 7  شماره 

صفحات  -

تاریخ انتشار 2016